Non-invasive systems for large animals
emka TECHNOLOGIES offers wired and wireless systems to measures blood pressure and ECG separately or concurrently in large animals during toxicology studies:
- emkaPACK4G for freely moving subjects
- nibpSNAPSHOT for restrained subjects
emkaPACK4G for freely moving subjects
With emkaPACK4G telemetry system, physiological measurements are captured non-invasively and radio-transmitted by Bluetooth, to a receiver.
A classic system is made of:
- One external transmitter, worn by each subject, into a jacket.
- One or several telemetry receivers, positioned in the animals’ room, within 10 meters distance from their associated transmitters.
Each subject is therefore free to move, single or group-housed in its room, during the acquisition (max. 32 to 48 subjects per room).
nibpSNAPSHOT for restrained subjects
nibpSNAPSHOT non-invasively measures oscillometric blood pressure and 7-lead ECG (6 standard leads, 1 chest lead) separately or concurrently in restrained dogs and primates during toxicology studies:
- Self-contained, hand-held measuring device
- Direct link to PC through USB connection
- Sampling frequency: 1000Hz
- Input pressure range: 0 to 300 mmHg
- User-adjustable measurement cycle (inflation and end-cycle pressure; 3 deflation speeds)
- Cuffs available in different sizes to adapt subject type and size (support for third-party cuffs)
The whole system is compact, as a single receiver can communicate with up to 16 transmitters, and is powered and transmits data through a single Ethernet cable.
Up to 17 signals (ECG, blood pressure and more!) can be recorded simultaneously from each animal, through various sensors plugged to the transmitter.
IOX2 software provides:
- Complete results in a GLP environment
- Mean, systolic and diastolic blood pressure
- Heart rate, pulse transit time (when ECG is recorded)
In depth, further NIBP and ECG analysis can be performed in ecgAUTO software.
This GLP compliant software allows researchers to perform field-tested,
fast, reliable & in-depth analysis of data generated during an experiment
Assessment of non-invasive telemetric blood pressure and electrocardiogram measurement in conscious dogs
Poster presented by GlaxoSmithKline, Society of Toxicology meeting, 2011
Development of a methodology to measure the effect of ergot alkaloids on forestomach motility using real-time wireless telemetry
Egert et al, Frontiers in chemistry, 2014
Evaluation of oscillometric and vascular access port arterial blood pressure measurement techniques versus implanted telemetry in anesthetized cats
Raphael J. Zwijnenberg et al. AJVR Vol 72, No. 8, August 2011
Inclusion of Blood Pressure Measurements in Canine Toxicology Studies
Emily Bailey et al, Poster presented by AstraZeneca, 2011