Implants for rats
easyTEL+ is a fully implantable digital system, that transmits physiological data from conscious freely moving laboratory animals. It can be remotely managed and configured.
Intended for use in preclinical research (primarily toxicology, pharmacology and safety pharmacology studies) and biodefense, the easyTEL+ implants are ideal for rodents > 200g such as rats.
Various models are available to meet your study needs and offer the ability to continuously record:
- Biopotential (ECG, EEG, EMG, EOG)*
- Blood pressure (Arterial and/or Left Ventricular Pressure)
- Respiratory rate**
- Acceleration from 3-axis accelerometer (activity)
*Electrocardiogram (ECG), electroencephalogram (EEG), electromyography (EMG), electrooculography (EOG)
**Derived from pleural or blood pressure, or diaphragmatic EMG
Customizable & remote control
Simple design & cost effective
easyTEL+ implanted telemetry is a customizable system, easy to implement and to manage, offering continuous reliable data recording during up to 175 days.
A variety of physiological signals, including biopotentials, blood pressure, respiratory rate, temperature, and postural activity data can be recorded, depending on the implant model.
Optional synchronized video can be recorded.
Up to 32 animals can be group-housed in the same room or cage, with no cross talk. Group-housing advantages include reduced stress and subject socialization, helping with the 3R’s* of research.
Quality of Signal (QoS) is available as its own signal, continuously monitoring the connection quality between the implant and the acquisition PC, and quickly detecting any change in the radiofrequency environment. QoS can be used to automatically differentiate between true events and data loss to avoid incorrect analysis (i.e. long RR intervals).
*Replacement, reduction, refinement
- Easily control implant state (on/off) without subject interaction.
- Use default settings or wirelessly customize sampling rate, resolution, power, transmission frequency, etc. before and after implantation.
Simple design and cost effective
easyTEL+ system design is compact, with a direct receiver-computer link, and easy to use, with no external antenna , for an easier implantation.
Implants are priced for a single use, eliminating the need for refurbishment and associated logistics (implants can be re-implanted as long as battery lasts).
Techniques & measurement
Physiological measurements are captured by a transmitter surgically implanted and wirelessly transmitted to a receiver within 3 to 5 meters distance.
With emka digital telemetry, the signal is already digitized by the transmitter. Therefore, when received by the telemetry receiver, it can be directly sent to the acquisition computer, via Ethernet.
Wireless technology is ideal to reliably transfer high volumes of data from a freely moving animal. Advantages associated with this technique are well known: Longer and better-quality data obtained from less stressed subjects, allowing compliance with 3Rs principles*.
Wireless implanted telemetry provides the unique ability to look into long-term physiological trends, as well as rare or isolated physiological events (arrhythmias, seizures, etc.).
*Replacement, reduction, refinement
Configuration & extensions
A typical setup includes implants, receivers, an ethernet switch and an acquisition computer. A single ethernet cable provides power and data transmission between the receiver and PC. Cameras can be added for synchronized video recording.
Software acquisition & analysis
easyTEL system runs with IOX2 software for signal acquisition and real time analysis.
ecgAUTO serves as a single analysis platform with à la carte modules to meet your unique analysis needs. Cardiovascular, neurological, and respiratory analysis utilize custom parameters and protocols to produce comprehensive data reports. Additional, advanced modules are available for interval analysis, arrhythmia and seizure detection, heart rate variability, and more.
|Animal weight||Group housing||Remote management|
|*Battery life refers to days of continuous recording. For easyTEL+ models, battery life is given for a data rate set to “high” and for biopotential standard sampling frequencies: 500Hz.
**ECG, EEG or EMG
And many more!