emka TECHNOLOGIES is offering on-demand trainings for your software of choice, to help you refine your use and hit the ground running when returning to your lab.
2020
All posts by Sandrine Lemouton
2020
Ex vivo studies provide valuable pharmacology insights across many domains.
Isolated organ or tissue systems give researchers complete environmental control (temperature, pressure, flow, perfusate, etc.) and remove the normal homeostatic regulation and whole animal influences. Such systems allow researchers to more quickly and accurately determine cause and effect in the absence of endogenous influence.
Tissue baths or myographs are widely used to study the effects of agonists and antagonists through the measurement of tissue contractility. Dose and concentration response curves allow for quantification of a drug’s pharmacological profile and the calculation of EC50’s.
LEARN MORE & DISCOVER HOW TISSUE BATH ARE USED IN PRECLINICAL RESEARCH
2020
Dear visitor,
We imagine the challenges you are presently facing due to COVID-19 outbreak, with disruption of your personal and professional lives, including the possible difficulty of working from home.
Hoping it can help you and be our modest contribution to everybody’s current efforts:
. We offer our IOX and ecgAUTO customers a three-month extra license at no charge, for example to help you working from home or speed-up your current studies.To obtain the license, simply contact us.
If you need a complementary training, we organize on-demand software training: Learn more here
. We stand ready to adapt our sales and delivery processes to special situations and users, for example through hardware and/or software rental or loan. We are also available to provide you with distant help in processing your data.
. We are working with our suppliers to secure our production and limit the risk of stock-outs and delivery delays.
. Our production and logistic teams are maintaining safe distances and clean workspaces to be able to continue to deliver orders made during the current pandemic.
We wish you and your loved one’s the best of health and success in your research.
User presentations
Join us during SOT annual meeting in Anaheim, California for our Exhibitor-Hosted Session:
How to “Hang Ten” on the Rodent ECG in Inhalation Toxicology
Alex Carll, Ph.D., M.S.P.H., Assistant Professor at the University of Louisville School of Medicine
The electrocardiogram (ECG) is a valuable tool for assessing cardiac pathophysiology and toxicity in both humans and rodents.
In this hosted session, Dr. Carll will introduce approaches to and reasons for monitoring the ECG during inhalation exposure studies in both mice and rats.
Attendees will learn how to:
- use ecgAUTO to identify arrhythmias and clean data for heart rate variability analyses.
- analyze ECG morphology to inform on conduction and arrhythmogenesis.
- navigate data overload, noise, the QT:RR, detection limits, and species differences.
- understand time- and dose-dependent relationships between ECG endpoints and inhaled toxins.
Please note that seating is limited.
We therefore encourage you to secure a place at this event by clicking here to access the registration form
 Room 206B,Anaheim Convention Center Anaheim, CA 92802, USA |
 
Wednesday March 18th, 2020 |
This session is an Exhibitor-Hosted Session. Although not an official part of the SOT Annual Meeting Scientific Program, its presentation is permitted by the Society.
How to find us?
User group
Unfortunately, due to the circumstances surrounding the coronavirus, we are very sorry to announce that we must cancel our User Group Meeting.
It will be postpone later in the year. We will keep you informed as soon a possible.
April 2, 2020
Leuven, Belgium
Join us for a day of scientific presentations and discussions to learn more about the flexiVent’s capabilities & flexivent applications and share your feedback with other users.
This user group meeting will be free of charge
Please note that seating is limited.
We therefore encourage you to secure a place at this event by clicking here to access the registration form
WHEN? Thursday April 2, 2020 – Lunch will be provided
WHERE? Leuven, Belgium (Park Inn by Radisson Hotel)
AGENDA:
| 9:00 a.m. | Registration. |
| 9:30 a.m. | Welcome and introduction. Frédéric Gagnon – emka TECHNOLOGIES |
| 9:45 a.m. | SCIREQ flexiVent to Measure Respiratory Mechanics. Kévin DEVIDAL – emka TECHNOLOGIES |
| 10:30 a.m. | New flexiWare features: reporting, lung volumes. Frédéric Gagnon – emka TECHNOLOGIES |
| 11:00 a.m | Negative Pressure Forced Expiration perturbation in mouse models of lung disease Dr. Jeroen Vanoirbeek – KU Leuven, Belgium |
| 11:20 a.m. | Troubleshooting flexiVent Data – Case Study (part 1). Mark Lawrence – SCIREQ Inc. |
| 11:40 a.m. | Lung function changes in mouse models of COPD Hannelore Van Eeckhoutte – University of Ghent, Belgium |
| 1:30 p.m. | Drug delivery with the flexiVent Application Mark Lawrence – SCIREQ Inc. |
| 2:00 p.m. | Impact of chronic exposure to e-cigarette vapors and comparison with cigarette smoke Philippe Gosset – Institut Pasteur Lille |
| 2:20 p.m. | Whole Body Plethysmograph and large animal studies Jérémy Appell – emka TECHNOLOGIES |
| 3:00 p.m. | Troubleshooting flexiVent Data – Case Study (Part 2). Mark Lawrence – SCIREQ Inc. |
| 3:30 p.m. | Open session: General discussion / product & software demonstration. |
| 4:00 p.m. | Closing Remarks. Frédéric Gagnon – emka TECHNOLOGIES |
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2020
March 5-6, 2020
Bethesda, Maryland – USA
The TBI Research Symposium 2020 is a platform for scientists from local organizations to exchange data and ideas that will advance research and treatment of traumatic brain injury (TBI).
As one of just 4 exhibitors during this symposium, we look forward to show our solutions for Neuro and CNS Research with the focus on TBI.
Animal models of TBI help scientists to study structural damage and functional deficits induced by brain injuries. Several studies demonstrated that long-term functional and structural changes take place up to 1 year after TBI.
emka’s solutions for TBI studies allow short but also long-term acquisition of various physiological parameters (EEG, EMG, blood pressure, respiration, temperature, activity) with:
Visit the symposium website.
User group
June 08–10, 2020
René Remie Surgical Skills Centre
Almere, The Netherlands
Transonic, René Remie Surgical Skills Centre (RRSSC) and emka TECHNOLOGIES are excited to join forces to present the first European Rodent, PV Loop & Cardiac Disease Model Workshop. The Workshop is designed to enable attendees to not only optimize their microsurgical skills, but also gain experience in Admittance-based PV measurements, and be introduced to common cardiac disease models.
Who should attend:
This course is designed for scientists and technicians who are new to rodent pressure-volume recording techniques or those who would like to refine their techniques.
The course will be from June 08-10, 2020 with one optional extra day for the induction of cardiac models (LAD occlusion and TAC).
2019
Please take note that our offices will be closed during holidays:
- Paris, France:
Closed from Wednesday, December 25th to Wednesday, January 1st. - Falls Church, VA, U.S.A:
Closed on Wednesday, December 25th and Wednesday, January 1st only.
Open all other days.
We wish you happy Holidays and our best wishes for the new year.
Meilleurs voeux!
2019
December 15-17, 201
Edinburgh, UK
Booth #14
emka TECHNOLOGIES is exhibiting at the Pharmacology 2019 annual meeting in Edinburgh.
If you plan to attend, I would be happy to meet you at our booth #14, to hear about your research and to discuss how our products can help meet your unique experimental needs.
Some of our products, designed to acquire physiological parameters from laboratory animals will be shown during the event:
- Whole body plethysmograph, for respiratory application, such as asthma
- ecgTUNNEL, for cardiovascular and respiratory pharmacology
- rodentPACK, for neuropharmacology studies
- Tissue bath systems, for ex vivo studies on isolated tissus
Contact us to schedule a meeting!
2019
December 03-06, 2019
Fukuoka, Japan
emka TECHNOLOGIES is exhibiting at the 42nd Annual Meeting of the Molecular Biology Society of Japan. Join us!
2019
December 06-10, 2019
Baltimore, USA
Booth #120
Join us in Baltimore for the AES2019 annual meeting to learn more about our solutions for epilepsy studies.
2019
November 17-20, 2019
Phoenix, AZ
USA
This year, we celebrate the 40th anniversary of the American College of Toxicology Annual Meeting in Phoenix, Arizona.
Join us to see how emka TECHNOLOGIES solutions can help you improving your toxicology studies and facing your daily challenges.
MOVING FROM PAPER TO DIGITAL
Come to discuss how we can accompany and guide you at all levels, whatever the modality chosen to acquire your parameters of interest. Learn more here
COMPLYING WITH SEND REGULATION
Submitting data in SEND format is required by the FDA starting January 2019.
To help you in this challenge, our software suite provides data tables under a SEND 3.1 compatible format for Respiratory, ECG and Vital signs domains.
Join us at our booth to discuss your needs and timeline.
Download the brochure 
Visite the website event.
2019
October 28, 2019
Washington, DC
USA
Join us to at the 6th Annual Meeting of the American Physiology Society, in Washington University, to discuss how our products can help meet your unique experimental needs, such as:
- Cardiovascular Applications
- Neuroscience Applications
- Respiratory Applications
- Perfusion Applications
- Isolated Organ Applications
User presentations
In recent years, cardiovascular safety scientists have adopted a number of analysis software platforms designed to streamline the evaluation of ECG and hemodynamic endpoints.
Post-processing with technologies such as pattern recognition can improve speed and accuracy of analysis using user-defined waveform libraries. While these technologies increase efficiency, the need to evaluate larger datasets (beat to beat), with increased depth (e.g. arrhythmia analysis), presents some conundrums: the need for significant level of human intervention, processing time, and most importantly, can be prone to high inter-user variability, a potential consequence of varying experience and analysis fatigue.
The goal of this study, presented by Mr Baublits from Amgen, during SPS Annual Meeting in Barcelona, is to leverage historical data to guide a novel pattern recognition algorithm in performing automated ECG and hemodynamic analyses.
Leveraging Machine Learning for Automated ECG and Hemodynamic Analyses 
2019
October 14-16 2019
Brighton, East Sussex, United Kingdom
Booth #7
This year, the main themes of the AIT conference are :
- Industrial chemicals
- E-Cigarettes
- Biopharmaceuticals
- In vitro assessments and alternatives
Join us to discuss these topics and how to improve your inhalation studies.
SMOKE & VAPE GENERATION
We will present the inExpose, that can be configured to generate cigarette smoke, e-cigarette smoke, vaping, hookah smoke, etc. to fit a wide range of applications. Various configurations are available:
- Single cigarette chamber
- Integrated cigarette smoking robot
- E-cigarette vape generation
DOWNLOAD PDF “ELECTRONIC CIGARETTES – FACTORS AFFECTING PARTICLE DEPOSITION”
DOWNLOAD “CONSIDERATIONS WHEN USING RESEARCH CIGARETTES IN PRECLINICAL STUDIES”
PRECISION DOSING
Precision dosing can be performed with the flexiVent’s ventilator-assisted aerosol delivery, in intubated small animals.
In conscious small subjects, breathing parameters and accumulated volume is monitored using plethysmography during exposure inhalation studies.
For large animals, monitoring during and post exposure can be performed by non-invasive telemetry.
2019
October 19-23, 2019
Chicago, IL, USA
Booth #1634
Neuroscience 2019 will take place at McCormick Place in Chicago. Join 30,000 colleagues from more than 70 countries at the world’s largest marketplace of ideas and tools for global neuroscience.
emka TECHNOLOGIES will be happy to show you implanted and head mounted systems for EEG acquisition.
Without any tethering cables, subjects are freely moving and emitting up to 4 noise-free EEG signals, for easy analysis of many neurological disorders: Sleep disorders, Seizure & epilepsy, Traumatic Brain Injury and many more.
As an example, our wireless rodentPACK system can be used to collect continuous video-EEG recordings and monitor for epileptiform discharges consistent with post-traumatic epileptogenesis, as explained in a recent publication by McGuire et al. in the Journal of Visualized Experiments (JoVE).
Looking forward to seeing you in Chicago!
User presentations
Join us during SPS annual meeting in Barcelona, Spain for our sponsored presentation with Amgen.
Leveraging Machine Learning for Automated ECG and Hemodynamic Analyses
Mr Joel Baublits, Senior Associate Scientist at Amgen
September 24, 2019 – 12:30-1:30 PM – Room 121
In recent years, cardiovascular safety scientists have adopted a number of analysis software platforms designed to streamline the evaluation of ECG and hemodynamic endpoints.
Post-processing with technologies such as pattern recognition can improve speed and accuracy of analysis using user-defined waveform libraries. While these technologies increase efficiency, the need to evaluate larger datasets (beat to beat), with increased depth (e.g. arrhythmia analysis), presents some conundrums: the need for significant level of human intervention, processing time, and most importantly, can be prone to high inter-user variability, a potential consequence of varying experience and analysis fatigue.
The goal of this study is to leverage historical data to guide a novel pattern recognition algorithm in performing automated ECG and hemodynamic analyses.
Methods:
Analysis was conducted using a developer build of ecgAUTO (v3.3.5.11, emka TECHNOLOGIES, Paris, France).
Amgen historical data was used to construct master waveform libraries for multiple assays including conscious non-human primates and conscious/anesthetized beagle dogs. Model waveform selection was based on a composite mode, marking the P, QRS, and T “zones” independently using different waveforms from the master library.
Reference compound datasets, including known Ikr and Na channel blockers, were used to test the algorithm. New output data was compared with historical data to determine performance.
Results:
The algorithm delivered high fidelity data that correlated well with historical analyses, suggesting that this new approach will be able to leverage historical data in a dynamic manner that can scale with increasing data volume. In addition, decreasing manual overreading will result in greater efficiency, delivering high quality data that is less prone to inter-user variability.
This session is a Sponsored Presentation. Although not an official part of the SPS Annual Meeting scientific program, its presentation is permitted by the Society
How to find us at SPS?
Safety Pharmacology 2019 Annual Meeting
September 23- September 26, 2019
Barcelona, Spain
Booth #605
User group
October 21-23, 2019
René Remie Surgical Skills Centre
Almere, The Netherlands
Transonic, René Remie Surgical Skills Centre (RRSSC) and emka TECHNOLOGIES are excited to join forces to present the first European Rodent, PV Loop & Cardiac Disease Model Workshop. The Workshop is designed to enable attendees to not only optimize their microsurgical skills, but also gain experience in Admittance-based PV measurements, and be introduced to common cardiac disease models.
Established partner Prof. René Remie will share his extensive microsurgical experience and enthusiasm with all attendees by encouraging the best surgical practices – learning the correct techniques and their implementation in attendees’ own laboratories as this course will take place at the René Remie Surgical Skills Centre.
Who should attend:
This course is designed for scientists and technicians who are new to rodent pressure-volume recording techniques or those who would like to refine their techniques.
The course language will be English. The host speaks several languages including: Dutch, English, German and basic French. Therefore, any one-to-one instruction can take place in one’s chosen/native language.
The course will be from October 21 to 23, 2019 with one optional extra day to provide attendees with an opportunity to learn how to introduce a myocardial infarction through ligation of the left anterior descending coronary artery (LAD), or to induce left ventricle hypertrophy by transverse aortic constriction (TAC).
Course fee and registration:
Three-day course fee: € 1980 (excl VAT).
Additional day: € 660 (excl VAT).
Course fee includes all course materials, coffee & tea, lunch and a group dinner on Day One. Participants will receive a certificate of the training (recognized in most EU countries).
For registration click here.
