In preclinical studies, understanding the potential toxicity of a test drug is crucial. Various toxicology studies are conducted at different stages of the drug development process, in order to identify unwanted effects or toxicities.
emka TECHNOLOGIES solutions are specifically designed to help researchers during general toxicology studies, and especially in vivo GLP repeat-dose cardiotoxicity studies.
Our integrated solutions allow for easy acquisition and analysis of ECG and blood pressure from rodents and large laboratory animals.
A smooth transition from paper to digital
In vivo studies offer a guideline for safe dosing and biomarkers to follow in clinical studies and any target organs affected by the compound. Whatever the modality chosen to acquire your parameters of interest, we’ll accompany and guide you at all levels, with an easy-to-use, flexible and fully GLP-compliant solution for your daily experiments.
The studyDESIGNER platform provides organization, data management, workflow guidance and automation for both the technicians and the study directors. The platform was designed to focus on secure noise free collection and automated post-processing to shorten time to reporting.
Save time and get reliable data using one of our available methods, integrated with studyDESIGNER solution. Widely used by many pharmaceutical companies and CRO, our well-proven solutions adapt to your needs:
- Just a few minutes for each snapshot measurement, even easier with wireless non-invasive systems: See our non-invasive solutions
- Ability to completely suppress animal manipulation with wireless implanted system
- Analysis fully automated with studyDESIGNER: Learn more about full capabilities
Comply with regulatory guidance
- Data consistency, reliability and integrity ensured by GLP modules
- SEND compatible output: Learn more
Implants for large animals
Toxicological testing of allogeneic secretome derived from peripheral mononuclear cells (APOSEC): a novel cell-free therapeutic agent in skin disease
SilvioWuschko et al, Scientific Reportsvolume 9, Article number: 5598 (2019)
Use of a non-invasive telemetry system (EMKA) for functional cardiovascular endpoints in toxicology studies
Derek Hunter et al
Oral repeated-dose toxicity studies of BIA 10–2474 in cynomolgus monkeys
Klaus Weber et al, Regulatory Toxicology and Pharmacology, 2019