knowledge base
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| QT interval |
Use in Drug Studies for FDA Approval
Since 2005, the FDA has required that new molecular entities are evaluated in a Thorough QT (TQT) study to determine a drug's effect on t… |
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| programmed electrical stimulation in mice - video protocol |
Na Li1, Xander H.T Wehrens1, 2
1Department of Molecular Physiology and Biophysics, Baylor College of Medicine, 2The Margare… |
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| why are AP measurements important and what is VAP? |
At the cellular lever, the action potential (AP) is the electrical signal that initiates the contraction of heart muscle.
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| real-time versus off-line processing |
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With the advent of powerful computers, it became possible to perform real-time data analysis. Not only could users see the signal being acquired and recorded in real time … |
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| telemetry means digital |
In recent years, preclinical research has evolved considerably to exploit the benefits of wireless communications. The most obvious manifestation has been the advent of telemetry systems (invasiv… |
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| Langendorff heart and working heart |
Two techniques are used to study the isolated mammalian heart, Langendorff heart (LH), named after Oscar Langendorff, and
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| effect of temperature and humidity in whole-body plethysmography |
In whole-body plethysmography, a differential pressure transducer measures the difference in the pressures between the subject chamber and a reference chamber. The signal is the sum of two flows … |
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system integration
