inputs

iox2 handles up to 128 inputs (64 physical + 64 calculated).

Each input acquires independently at rates ranging from 10 to 50,000 samples per second. For example, you could use 1Hz for temperature, 500 Hz for blood pressure, 1kHz for ecg.

Create one site for each of your experimental units (e.g. animals, isolated organs or tissues...).

Enter subject-relevant information for each site.

All software settings constitute a configuration, which can be saved for later use either unmodified or modified.

Analyzers are software modules that compute real-time parameters from input signals.

For example, an isolated heart site might have 3 analyzers: LVP (left ventricular pressure), SLOW (perfusion pressure), and ecg.

Site/Input/Analyzer assignment is intuitive, flexible, and GLP-compliant.

analyzer tuning
Tune analyzers according to preferences and to signal type. For example, adjust detection thresholds or percentage of drop for relaxation time measurements.

Analyzer settings can be adjusted while running the experiment. All settings, along with the time of implementation are stored in the log-book and in the master file.

Analyzers continuously send calculated parameters to tables and graphs.

Log according to time or events (pulse, contraction), based on single or average values.

data storage

Data storage sends calculated parameters to the data file. Store data according to time or events, with or without averaging.

For example, you can choose to display beat-by-beat values on screen, and store the average of the last 10 beats on disk every 5 seconds.

The storage mode can be changed during the experiment, from the keyboard or from the protocol.

Setting changes are recorded in the log-book and in the master file.

views for data information display

Build an unlimited number of full-screen views.
Each view is built to your preference, as a mosaic of various graphs and data tables.

All views and settings are saved with the configuration.

data streaming

Data streaming records raw data on hard disk. Streaming starts and stops independently on each site. Use streaming if you intend to replay an experiment at another time.

Raw data file size is optimized by adjusting acquisition rates of each input.

iox2 can replay data files from previous experiments. The replay function allows data to be reprocessed with modified analyzer settings as well as period-specific replay referring to original event marks.

• choice of two replay modes:
  
  " integral-replay " : the site-file is replayed with all original event markers and exactly like the experiment was performed (only analysis settings and/or storage rates can be changed)
  
  " free-replay " : identical to integral-replay except that new event markers can be added
• adjustable replay speed and start point : replay in either mode up to 10 time faster, from any time point in your experiment, or from a specific marker (i.e. third occlusion)

Replay generates a new site-file, similar in form to the original site-file. This ensures that archived files all have identical content and format.

The review function displays signal traces and calculated derived parameters.

• • review beat-by-beat values
• •verify where calculated parameters were computed by the analyzers
• •select a specific beat and view corresponding derived parameters in table format
• •perform additional on-line measurements from cursors
• •export raw data values in text format for further analysis in any spreadsheets

• • user name and status
• • study information
• • configuration
• • raw data (if recorded)
• • beat-by-beat points of measurement when raw data is available
• • calculated data
• • log-book
• • summary of errors encountered during the experiment

To ensure data integrity, a site-file can only be accessed by emka TECHNOLOGIES's software to:

• • load into iox2 for replay and/or review
• • load into datanalyst for post-processing, data extraction, and/or review
• • load into ecgAUTO to perform automated ecg analysis
• • extract all or part of a configuration when building a new iox2 configuration
• • extract calculated data to text files

A4 printer
Connected to a standard printer (typically an A4 laser printer), iox2 produces fully documented screen snapshots, protocol printouts, etc. This printer can also be set to produce, at regular time intervals, a printout of a selected view, for easy archiving of waveshape changes over time.

cardiograph
In compliance with regulatory requirements, iox2 produces fully documented cardiograph-type printouts using a standard printer (typically an A4 laser printer). This feature is useful for ecg printouts for which manual measurements are needed for validation and documentation purposes.

chart recorder
While outputting to a standard printer, iox2 can also simultaneously drive a large size (A3) listing paper printer, as a better alternative to the traditional chart recorder. This “powered” chart-recorder produces, at up to 50mm/min, graphs of raw or calculated data, with full experiment and event information.