emka TECHNOLOGIES S.A.
59, bd. Général Martial Valin
75015 Paris - France
tel: + 33 (0)1 40 60 76 00
fax: +33 (0)1 40 60 65 55
e-mail: emka@emka.fr
emka TECHNOLOGIES Inc.
307 Annandale Road, suite 203
Falls Church, VA 22042 - USA
tel: +1 (703) 237-9001
fax: +1 (703) 237-9006
e-mail: emkatech@emkatech.com
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emka TECHNOLOGIES' applications for safety pharmacology and toxicology studies
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> home > applications > telemetry in rodents

 

telemetry in small animals

emka TECHNOLOGIES offers three solutions for telemetry studies in small animals such as mice, rats and rabbits:

Subjects are conscious and freely moving in the three cases.

rodentPACK

rodentPACK is a cost-effective solution for running telemetry studies in animals 250g and upwards. Applications are varied, e.g. sleep and epilepsy studies, ecg recording.

During surgery, biopotential electrodes are implanted and a connector is mounted on the skull. Once the head connector is secure, the rodentPACK transmitter can be connected and disconnected as necessary for each recording session.

Upto 8 signals are acquired from each animal: 

  • 2 eeg signals 
  • 2 emg/ecg signals (any combination) 
  • 3-axis acceleration (for postural information)
  • total acceleration.


Telemetry Research implants

Implants from Telemetry Research can be used in animals 200 g and upwards. Several transmitter implants are available for acquiring different parameters such as biopotentials, pressure and temperature. Of note, implants are available for the acquisition of sympathetic nerve activity with a sampling rate of 8 kHz. 

In this system, customers recharge the transmitter batteries themselves.  The recharging device is a flat platform on which the animal cage can be placed. This makes it possible to obtain a lifetime recording!

The telemetry hardware is open so you can use any software to acquire your data. 


DSI  implants

Data Sciences International (DSI) offers a wide range of transmitter implants for the measurement of different parameters such as biopotentials, pressure and temperature.

iox may be used for acquisition from DSI implants - this is is possible because of the openART software interface. The analysis files can subsequently be analyzed in ecgAUTO.

Long-term studies with implanted animals are used to study: 

  • the long-term effects of a pharmacological product
  • cardiovascular remodelling following surgical intervention 
  • the development of pathologies in transgenic mice (or other animals)
  • etc


example of use

Implanted rodents are used by the cardiovascular phenotyping laboratory of the Montreal Heart Institute. Their setup includes: 

  • mice equipped with 16 ecg implants and 8 bp implants
  • rats equipped with 8 ecg implants, 8 bp implants, and 8 implants measuring ecg and bp
  • workstations with iox and ecgAUTO. All ecg intervals and segments are measured at a sampling rate of 1000 Hz

 

 

telemetry with DSI and iox software:

Download the telemetry integrated systems brochure. Download the DSI telemetry and emka TECHNOLOGIES iox software brochure. Download the mice studies brochure.
emka telemetry integrated systems brochure emka DSI telemetry and emka TECHNOLOGIES iox software brochure emka mice studies brochure
download download download



 

telemetry and ecg mice restrainers

telemetry and ecg mice restrainers

complete seamless solution from mouse to report !
ecg
TUNNEL to house subject

  • animal is gently restrained within ecgTUNNEL
  • range of sizes to accommodate from neonate to adult mice

noise free, wireless, emkaPACK ecg amplifier and transmitter

  • battery operated
  • 1 to 6 ecg leads
  • direct connection to ecgTUNNEL

Download the emka ecgTUNNEL mouse restrainers brochure.



  case studies
CHALLENGE: Some signals are not easy to measure directly either because access is limited&…

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